Monday, June 4, 2012

Seroquel Overdose Side Effects and Management of Overdose

By Andreas Gratschmeier


Quetiapine is an antipsychotic drug marketed under the brand Seroquel. This kind of substance is required to take care of psychiatric disorders. It may be utilized safely and securely whenever the recommended amount is taken. When an individual overdoses on Seroquel, it can cause serious adverse reactions. The side effects of a seroquel overdose may be life-threatening and ought to be treated promptly to prevent irreversible problems or death.

Seroquel should generally be delivered with a 1st dose of 25 mg. Pursued by raises in batches of 25-50 milligrams on the second and third day to a target dosage range of 300 to 400 mg daily by the fourth day. Extra dosage alterations ought to commonly occur at time periods of not less than two days, as a stable condition for Seroquel in the standard individual would not be accomplished for about 1-2 days.

In clinical studies tests were made using approximated dosages starting from 1200 mg to 9600 mg with zero deaths. Generally, reported warning signs were those caused by an overstatement of the drug's recognized medicinial side effects, i.e. sleepiness and sedation, tachycardia as well as hypotension. One situation, involving an estimated overdose of 9600 milligrams, has been connected with hypokalemia and 1st degree coronary heart block. There are very rare reviews of overdose of Seroquel leading to loss of life or coma in post-marketing experience.

Adverse reactions of a seroquel overdose can include: Fast heart beat (also known as tachycardia), which could raise the likelihood of stroke or heart attack, interrupt the regular functionality of the heart as well as result in unexpected heart attack. Somebody who overdoses on Seroquel could have difficulties keeping up and sensing great sleepiness. Fainting occurs when somebody briefly loses consciousness. A seroquel overdose can result in dizziness, which is a expression that relates to feelings of weakness, unsteadiness, faintness and lightheadedness. Fatigue is described as too little power or sense of exhaustion in the course of physical activities.

In the instance of severe overdosage establish and maintain an airway and make certain sufficient oxygenation and ventilation is available. Gastric lavage and administration of activated charcoal together with a laxative is highly recommended. The possibility of obtundation, seizure or dystonic reaction of your head and also your neck immediately after an overdose could increase the likelihood of aspiration with induced throwing up. Cardiovascular monitoring ought to begin right away and should incorporate constant electrocardiographic monitoring in order to discover possible arrhythmias.




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